Gonadorelin Acetate

Research Specifications

Sequence:
Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
CAS:
33515-09-2 (acetate)
Molecular weight:
1182.29 Da
Form:
Acetate salt, lyophilized
Purity:
≥98% HPLC verified

Gonadorelin Acetate

GnRH decapeptide (synthetic LHRH)

CAS: 33515-09-2

~4 min

Half-life

Clinical PK

10 aa

Decapeptide

Native GnRH sequence

1971

First identified

Schally/Guillemin

Receptor Targets

GnRHRPituitary gonadotroph → LH + FSH release
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Approved

Approved for diagnostic stimulation testing

FDA-approved as a diagnostic agent for evaluating HPG axis function. Used clinically for hypogonadotropic hypogonadism diagnosis and pulsatile restoration therapy.

Also Known As

GonadorelinGnRHGonadorelin acetateLuteinizing hormone-releasing hormoneLHRHLH-RH

Reconstitution & Dosing Guide

BAC Water

Variable (1 mg/mL typical)

Final Concentration

1 mg/mL

Per Dose

100 μg = 0.1 mL · 20 μg = 0.02 mL (pulsatile)

Pulsatile dosing preserves HPG axis; continuous dosing paradoxically suppresses it

Published References

  1. 1.
    Schally AV, Arimura A, Kastin AJ, et al.. Gonadotropin-releasing hormone: one polypeptide regulates secretion of luteinizing and follicle-stimulating hormones. Science (1971) PMID: 4940442

Research Use Only. This product is intended for in-vitro laboratory research only. Not for human consumption, injection, or therapeutic use. Not medical advice. Always consult applicable regulations in your jurisdiction.

Price Comparison

SupplierPurityPriceShipping
our verified supplier>98% HPLC$44.99Free over $200
Generic Research SuppliersVaries (often <95%)Similar–HigherVaries
Pharmaceutical (Rx only)Pharmaceutical gradeNot available for researchRx required

Gonadorelin Acetate

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