Part of Clavicular's Looksmaxxing Stack
TB-500 complements BPC-157 in the looksmaxxing recovery stack. Often recommended alongside Clavicular's core protocol for enhanced healing.
Research Specifications
- Active Sequence:
- Ac-LKKTETQ (core actin-binding motif)
- Full Name:
- Thymosin Beta-4 fragment (synthetic analogue)
- Molecular Weight:
- 2174.5 Da
- Form:
- Lyophilized powder
- Purity:
- ≥98% (HPLC verified)
- Storage:
- −20°C long-term / 4°C up to 4 weeks reconstituted
- Reconstitution:
- Bacteriostatic water
TB500 10mg
Synthetic thymosin beta-4 fragment. Researched for actin dynamics, satellite cell activation, and systemic tissue repair.
Featured in Clavicular's looksmaxxing protocol
43
Amino Acids (Tβ4)
Full native peptide
2174 Da
Molecular Weight
NCBI PubChem
Ubiquitous
Natural Distribution
Found in all nucleated cells
Why Clavicular Uses This Peptide
TB-500 complements BPC-157 in the looksmaxxing recovery stack. Often recommended alongside Clavicular's core protocol for enhanced healing.
See Clavicular's complete looksmaxxing stack →Actin Sequestration & Satellite Cell Activation
TB-500 is a synthetic analogue of the active region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid peptide found in nearly all human and animal cells. Its primary mechanism is G-actin sequestration via the Ac-LKKTETQ motif — this prevents actin polymerization in a way that promotes cell migration, tissue repair, and angiogenesis. TB-500 also activates satellite cells (muscle stem cells), upregulates metalloproteinases for ECM remodeling, and has anti-inflammatory properties.
Research Highlights
Muscle Repair & Satellite Cell Activation
Tβ4 and its analogues have been shown to promote satellite cell differentiation in in vitro and animal models, supporting skeletal muscle regeneration after injury. This makes TB-500 relevant to research involving caloric restriction or training-induced muscle damage.
Cardiac & Vascular Research
Multiple studies have examined Thymosin Beta-4's effects on cardiac repair post-infarction, demonstrating reduced cardiomyocyte apoptosis and improved neovascularization in mouse models. TB-500's angiogenic properties derive from its upregulation of VEGF and other pro-angiogenic factors.
Anti-inflammatory Properties
TB-500 reduces levels of pro-inflammatory cytokines including TNF-α and IL-1β in animal inflammation models. This anti-inflammatory action complements its tissue repair effects, particularly in chronic injury research contexts.
Research FAQ
What is the difference between TB-500 and BPC-157?
Why is TB-500 in Clavicular's recovery stack?
How is TB-500 different from native Thymosin Beta-4?
Research Use Only. This product is intended for in-vitro laboratory research only. Not for human consumption, injection, or therapeutic use. Not medical advice. Always consult applicable regulations in your jurisdiction.
Price Comparison
| Supplier | Purity | Price | Shipping |
|---|---|---|---|
| Apollo (via ClavTides) | >98% HPLC | $59.99 | Free over $200 |
| Generic Research Suppliers | Varies (often <95%) | Similar–Higher | Varies |
| Pharmaceutical (Rx only) | Pharmaceutical grade | Not available for research | Rx required |
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TB500 10mg
$59.99