Research Specifications
- Structure:
- Soluble ActRIIB extracellular domain + IgG1 Fc
- Molecular weight:
- ~80 kDa (dimer)
- Developer:
- Acceleron Pharma (historical)
- Vial:
- 1mg lyophilized
- Purity:
- ≥98% HPLC verified
ACE-031 1mg
Recombinant ActRIIB Fc fusion protein
CAS: 1234-56-7
Myostatin
Primary ligand target
GDF-8 trap
Fc-fusion
Structure class
Soluble receptor
Discontinued
Clinical development
Acceleron 2013
Phase 2 discontinued 2013 (vascular safety)
Acceleron Pharma halted DMD Phase 2 trials in 2013 due to telangiectasias and epistaxis. No further clinical development. Remains a research compound for myostatin axis biology.
Also Known As
Reconstitution & Dosing Guide
BAC Water
0.5mL
Final Concentration
2 mg/mL
Per Dose
0.5 mg = 0.25 mL
Gentle handling — Fc-fusion proteins are shear-sensitive; no vortexing
Published References
- 1.Campbell C, McMillan HJ, Mah JK, et al.. Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy. Muscle & Nerve (2017) PMID: 27464031
- 2.Attie KM, Borgstein NG, Yang Y, et al.. A single ascending-dose study of muscle regulator ACE-031 in healthy volunteers. Muscle & Nerve (2013) PMID: 23169855
Research Use Only. This product is intended for in-vitro laboratory research only. Not for human consumption, injection, or therapeutic use. Not medical advice. Always consult applicable regulations in your jurisdiction.
Price Comparison
| Supplier | Purity | Price | Shipping |
|---|---|---|---|
| our verified supplier | >98% HPLC | $179.99 | Free over $200 |
| Generic Research Suppliers | Varies (often <95%) | Similar–Higher | Varies |
| Pharmaceutical (Rx only) | Pharmaceutical grade | Not available for research | Rx required |
Buy Peptides Compounds
ACE-031 1mg
$179.99