Research Specifications
- Sequence:
- D-retro-inverso 27-mer from FOXO4 p53-binding domain
- Molecular weight:
- ~3000 Da
- Vial:
- 10mg lyophilized
- Purity:
- ≥98% HPLC verified
FOXO4-DRI 10mg
FOXO4 D-retro inverso senolytic peptide
CAS: 1303491-30-2
D-retro-inverso
Structural design
Baar 2017
Senolytic
Mechanism class
Selective apoptosis
Cell 2017
Landmark paper
de Keizer lab
Receptor Targets
FOXO4Competitive displacement from p53
p53Released to mitochondria → apoptosis (senescent cells only)
$134.99In Stock
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Preclinical
Preclinical senolytic research
Landmark 2017 mouse data. No human clinical trials as of 2024. Active area of senolytic peptide research.
Complementary Compounds
Also Known As
FOXO4-DRIFOXO4-D-Retro-InversoFOX04-D-Retro-InversoSenolytic peptide
Prep & Cycle Schedule
BAC Water
2mL
Final Concentration
5 mg/mL
Per Dose
1 mg = 0.2 mL · 5 mg = 1 mL
Pulse dosing typical — alternate days or 2–3× per week, not daily
Published References
- 1.Baar MP, Brandt RMC, Putavet DA, et al.. Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. Cell (2017) PMID: 28340339
Research Use Only. This product is intended for in-vitro laboratory research only. Not for human consumption, injection, or therapeutic use. Not medical advice. Always consult applicable regulations in your jurisdiction.
Price Comparison
| Supplier | Purity | Price | Shipping |
|---|---|---|---|
| our verified supplier | >98% HPLC | $134.99 | Free over $200 |
| Generic Research Suppliers | Varies (often <95%) | Similar–Higher | Varies |
| Pharmaceutical (Rx only) | Pharmaceutical grade | Not available for research | Rx required |
Buy Peptides Compounds
FOXO4-DRI 10mg
$134.99